Flash Chromatography Products
Flashmaster systems
Isolute Flash cartridges
Post-synthesis sample work is a routine part of the purification process and typically includes scavenging excess reagents, using catch & release techniques to remove impurities, aqueous extraction, removing water and/or filtration. Once a sample has been cleaned up, it is typically purified by flash chromatography. Biotage designs, develops, and manufactures products for both sample preparation and flash purification.
For workup, products include scavenging media and cartridges, catch & release media and cartridges, drying media and cartridges, phase separators, and filtration columns.
For purification, a wide variety of flash systems and flash cartridges are available.
Flashmaster systems
FlashMaster™ Personal and FlashMaster Personal Plus™ Pump-based FLASH Purification Systems
These entry-level flash systems use electric pumps to deliver solvent. These isocratic systems can be upgraded to gradient operation with the optional GradMaster™ and switch box.
The FlashMaster Personal is a single-cartridge system capable of purifying upwards of 5 grams of sample per run.
The FlashMaster Personal Plus is a two-cartridge system capable of using two cartridges in series to purify difficult samples.
The second cartridge can also be used to load sample to the primary purification cartridge.
ISOLUTE® FLASH Cartridges
Based on a simple syringe-barrel design, ISOLUTE FLASH cartridges are utilized “on-line” with manual or automated FlashMaster™ systems or “off-line” with a FlashVac™ Sample Processing Station.
ISOLUTE FLASH cartridges are available in several sizes and media quantities from 5 g to 100 g. Stationary phase availability includes KP-SIL, ISOLUTE C18 (EC), ISOLUTE NH2 and ISOLUTE SCX-2.
On-line purification of synthetic sample mixtures is easy and direct using FlashMaster systems and cartridge adapters. Off-line applications include sample cleanup or sample workup such as scavenging and catch & release.
Features and Benefits
- High surface-area media ensures high capacity and efficiency
- Uniform particle-size distribution generates narrow elution bands
- Nine size offerings accommodate purification of milligram to multigram sample loads
- Several media selections provide selectivity choices for optimal purification and cleanup
- FLASH silica available in TLC format improves optimization and analysis
- Polyethylene cartridge barrels reduce product cost and are disposable
- Cartridges meet 21 CFR 177.1520 regulations for extractables
- Prepacked cartridges eliminate hazards of loose silica and are safer than glass columns