The AVATAR™ Cell Control System lets you generate your cells of interest in a microenvironment array and optimize to a growth rate, functional activity or phenotypic change of interest. You’ll also be able to transfect cells with better efficiency, expand them faster and derive just the cells you need, exactly when you need them.
Oxygen and pressure have distinct physiological effects and both play important but independent roles in the cellular microenvironment. Under hypoxic and pressurized culturing conditions, changes are seen in cell morphology, gene and protein expression. Modulation of atmospheric pressure affects the mechanobiology of cell function during culture, and has profound effects on cell homeostasis and metabolism.
The human body is made up of diverse microenvironments that influence the behavior and molecular profiles of cells. Tissues are hypoxic and pressurized. They function at a much lower oxygen level than the basic air environment in typical incubator, and interstitial fluid pressures vary depending on the tissue and organ type.
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